A comparison study of ondansetron and palonosetron for the prevention of postoperative nausea and vomiting

A comparison study of ondansetron and palonosetron for the prevention of postoperative nausea and vomiting in women patients using intravenous patient-controlled analgesia

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CRIS

Registry ID

KCT0000809

Enrollment

204

Registered

2013-07-27

Start date

2013-08-05

Completion date

Unknown

Last updated

2019-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Drug : Group Ond : ondansetron 8 mg (Zofran?) IV 30 min before end of surgery Group Pal : palonesetron 0.075 mg (Aloxi?) IV 30 min before end of surgery

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: 1) Heathy women patients who scheduled elective operation umder general anesthesia 2) 20-70years old patients who scheduled to receiv an intravenous patient-controlled analgesia using fentanyl

Exclusion criteria

Exclusion criteria: Paients who have significant respiratory, cardiovascular, gastrointestinal, and cerebral, renal and hepatic disease. Patient who experienced emesis or received antiemetics or steroids within 24 hours. Patients who have history od drug or opioids addiction, Patients who can not communicated, Pregnant woman, morbid obesity

Design outcomes

Primary

Measure	Time frame
PONV incidence during the 24 hours postoperative	—

Secondary

Measure	Time frame
nausea severity during the 24 hours postoperative;the incidence of rescue antiemetics;patients' satisfaction;incidence of side effects	—

Countries

Korea, Republic of

Contacts

Public ContactSoon Im Kim

Soon Chun Hyang University Hospital Seoul

Outcome results