Research on the pschological wellbeing of HIV patients

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

CRIS

Registry ID

KCT0000765

Enrollment

100

Registered

2013-06-05

Start date

2013-03-27

Completion date

Unknown

Last updated

2019-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Drug : Initial dosage of mirtazapine and escitalopram are determined by the investigator's clinical decision. maximum initial dosage are 10mg of escitalopram, 15mg of mirtazapine. And then usual dosag

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1)Aged 20 or older patient who were diagnosed as HIV infection by western blot 2)HAMD-17>=14 3)Diagnosed as major depressive disorder, dyathymic disorder, depressive disorder not otherwise specified by the DSM-IV criteria via psychiatrist's interview 4)Can understand the objective of the study and sign informed consent 5)If the subject is woman of childbearing age, the patient who does not plan to become pregnant and who uses appropriate contraceptive method 6)With ability to perform the procedure of study, administration of drug, visit to thi clinic as study protocol or with caretaker or clear officer who can help to perform the study procedure((eg, family, social workers, social work, volunteer, or nurse)

Exclusion criteria

Exclusion criteria: 1)history of significantly unstable or uncontrollable medical condition, 2)unavailability to perform the psychiatric examination due to an acute physical illness 3)currently diagnosed or had history of other psychiatric disorder on DSM-IV Axis I : bipolar disorder, schizophrenia, schizoaffective disorder, schizophreniform disorder, psychotic disorder NOS) 4)history of organic mental disorder, epilepsy or other convulsive disorder 5)history of prescribing anticonvulsant 6)patients needed hospitalization due to the psychiatric condition other than depression( abuse/dependence of alcohol/other substance) 7)history of ECT for current depressive episode 8)Pregnancy or breastfeeding 9)history of unknown or uncontrolled neutropenia

Design outcomes

Primary

Measure	Time frame
Hamilton depression rating scale;Hospital anxiety and depression scale;Clinical Global Impression	—

Secondary

Measure	Time frame
Social and Occupational Functioning Assessment Scale (SOFAS);Fatigue Severity Scale (FSS)	—

Countries

Korea, Republic of

Contacts

Public ContactHee-JU Kang

Chonnam National University Hospital

Outcome results