Comparison of effects of intraoperative esmolol and ketamine on remifentanil-induced hyperalgesia in patients undergoing laparoscopic cholecystectomy

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

CRIS

Registry ID

KCT0000717

Enrollment

Registered

2013-04-05

Start date

2012-09-03

Completion date

Unknown

Last updated

2019-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Drug : Anesthesia was equally maintained with sevoflurane and 4 ng/ml of remifentanil in all patients. Ketamine (0.3 mg/kg) was injected and followed with a continuous dosage of 3 mcg/kg/min in the ke

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Must satisfy the following two criteria 1.20 year- 70 year adult 2.ASA(American Society of Anesthetists) Physical Classification Grade 1 or 2

Exclusion criteria

Exclusion criteria: 1.hepatic diseases 2.renal diseases 3.DM 4.cardiac diseases 5.recent administration of opioids or beta blockers 6.asthma 7.airway hypersensitivity 8.diseases related to airway 9.allergies to drugs

Design outcomes

Primary

Measure	Time frame
VAS(visual analogue scale) in recovery room;Postoperative fentanyl requirement in recovery room	—

Secondary

Measure	Time frame
postoperative nausea and vomiting, and sate of sedation	—

Countries

Korea, Republic of

Contacts

Public ContactCheol Sig Han

Hallym University Medical Center-Kangnam

Outcome results