Study of intralymphatic immunotherapy

A randomized, double-blind, parallel, single organ study for analysis of clinical effect after allergen injection into inguinal lymph node in allergic rhinitis patients

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

CRIS

Registry ID

KCT0000698

Enrollment

Registered

2013-03-06

Start date

2013-06-03

Completion date

Unknown

Last updated

2019-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Drug : Study group: Tyrosine S (Allergy Therapeutics, UK) for DP and DF, 0.1ml, injection into inguinal lymph node, 3 times with one-month interval Control group: saline injection at same site

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: ? rhinitis symptoms, more than 3 months ? no medication, recent 2 weeks ? house dust mite positive based on skin prick test

Exclusion criteria

Exclusion criteria: ? patients with chronic hepatitis, autoimmune disease, or immunodeficiency ? patients who take ß-blocker or ACE inhibitor ? pregnant

Design outcomes

Primary

Measure	Time frame
allergic rhinitis symptom score	—

Secondary

Measure	Time frame
skin prick test, CAP score	—

Countries

Korea, Republic of

Contacts

Public ContactJae Hoon Cho

Konkuk University Medical Center

Outcome results