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Comparing effects of ramosetron and ondansetron for the prevention of postoperative nausea and vomiting after atrabismus surgery

Ramosetron reduces postoperative nausea after adult strabismus surgery: a prospective, randomized, double-blinded study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CRIS
Registry ID
KCT0000688
Enrollment
240
Registered
2013-02-27
Start date
2011-04-08
Completion date
Unknown
Last updated
2019-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Drug : Recruited patients were allocated randomly to receive one of the following three drugs at the end of surgery: intravenous (IV) placebo (normal saline), ondansetron (4 mg), or ramosetron (0.3 mg

Sponsors

The Catholic University of Korea, Seoul St. Mary's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: American Society of Anesthesiologists (ASA) physical status I and II, and scheduled for strabismus surgery under general anesthesia were enrolled

Exclusion criteria

Exclusion criteria: Patients who took any analgesics, steroids or antiemetics 24 h before surgery, or who had gastrointestinal diseases, previous experience of PONV, or severe motion sickness were excluded.

Design outcomes

Primary

MeasureTime frame
postoperative nausea and vomiting

Secondary

MeasureTime frame
adverse effects of ramosetron and ondansetron

Countries

Korea, Republic of

Contacts

Public ContactJin Joo

The Catholic University of Korea, Seoul St. Mary's Hospital

jiyo1004@catholic.ac.kr+82-2-2258-6162

Outcome results

None listed

Source: CRIS (via WHO ICTRP) · Data processed: Mar 3, 2026