None listed
Conditions
Interventions
None listed
Sponsors
Yonsei University, Wonju Severance Christian Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: (1) Adult male and female less than the age of 70 over the twenty years old. (2) The patients and their families satisfied the revised Bethesda guideline 2004 version (3) patients and their families who diagnosed colorectal cancer with MSI positive or abnormal DNA repair protein or MMR gene mutation (4) Patients and their families who diagnosed with FAP or FAP subtype (5) Patients and their families who diagnosed with colon polyposis syndrome or polyposis syndrome suspect (6) Agree to paticipate the clinical trial
Exclusion criteria
Exclusion criteria: (1) The medical condition that cannot perform the clinical trial (2) Disagree to the clnical trial (3) Patient who paticipate another clinical trial
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The clinical characteristic of familial colorectal cancer and intestinal polyposis syndrome;The genetic characteristic of familial colorectal cancer and intestinal polyposis syndrome | — |
Secondary
| Measure | Time frame |
|---|---|
| Genetic test of MSI, MMR IHC(MLH1, MHS2, MSH6, PMS2) for familial colorectal cancer;Genetic test of APC, MYH, SKT11, SMAD/DPC4, PTEN for intestinal polyposis syndrome | — |
Countries
Korea, Republic of
Contacts
Public ContactHong Park
Yonsei University, Wonju Severance Christian Hospital
Outcome results
None listed