Up-and-down determination of the 95% effective dose of remifentanil for prevention of coughing response to the endotracheal tube during extubation in tonsillectomy or adenoidectomy in children

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CRIS

Registry ID

KCT0000653

Enrollment

Registered

2013-02-04

Start date

2012-10-29

Completion date

Unknown

Last updated

2019-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Drug : All included patients will receive remifentanil continuous infusion via intravenous route which is already placed before admit operating room. The duration of remifentanil infusion is from the

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Children aged from 3 to 12 years who undergoing elective tonsillectomy and/or adenoidectomy

Exclusion criteria

Exclusion criteria: - any other systemic underlying disease - presence of symptomes of upper airway infection within 2 weeks before surgery - surgery prolongs more than 2 hours - unexpected intraoperative hemorrhage or complications - history of allergic reaction to opioid

Design outcomes

Primary

Measure	Time frame
cough response	—

Secondary

Measure	Time frame
hemodynamic variable;extubation time	—

Countries

Korea, Republic of

Contacts

Public ContactYonghee Park

Seoul National University Hospital

Outcome results