None listed
Conditions
Interventions
Drug : Randomization was centralized using an online, computer-generated randomization system before the MDRDRplus assay results are identified. Patients were stratified into two groups according to t
Sponsors
Asan Medical Center
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Adult patients (= 18 years of age) (i) with culture-confirmed pulmonary TB or (ii) positive sputum acid-fast bacillus (AFB) smear with imaging findings consistent with pulmonary TB were included. We included patients who had not yet received treatment for TB or had been under treatment for less than two weeks.
Exclusion criteria
Exclusion criteria: Exclusion criteria were as follows: (i) history of TB resistant to INH and/or RIF; (ii) inability to receive standard four-drug treatment because of an underlying condition, such as liver or kidney disease; (iii) any condition that may prove fatal during the course of anti-TB treatment, such as advanced-stage cancer; (iv) combined extrapulmonary TB requiring prolonged treatment (e.g., TB meningitis, bone and joint TB); and (v) imaging findings compatible with typical findings of lung disease due to nontuberculous mycobacterium, despite a positive AFB smear in cases for which the AFB culture result was not yet available.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The proportion of patients who achieved treatment success at the end of treatment. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1-year recurrence | — |
Countries
Korea, Republic of
Contacts
Public ContactTae Sun Shim
Asan Medical Center
Outcome results
None listed