None listed
Conditions
Interventions
None listed
Sponsors
Samsung Medical Center
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Infection caused by multidrug-resistant pathogens for which there is no effective alternative other than ciprofloxacin 2. Infection attributable to ciprofloxacin-susceptible pathogens in children with life-threatening allergy to alternative agents 3. Parenteral therapy is not feasible and no other effective oral agent is available except ciprofloxacin 4. Immunocompromised pateints with persistent neutropenic fever who have hypersensitivity to beta-lactam antibiotics 5. Immunocompromised patients with septic shock despite broad-spectrum antibiotics therapy, which is suspected serious infection caused by multidrug-resistant pathogens
Exclusion criteria
Exclusion criteria: 1. Subject with history of hypersensitivity to quinolones 2. Subjects with epilepsy 3. Subjects with history of tendonitis or rupture of tendon associated with the use of quinolones 4. Subjects taking tizanidine medication 5. Subjects taking keotifen medication 6. Subjects with history of/current pronlonged QT syndrome 7. Subjects who are pregnant or breast-feeding mother 8. Subjects with infections caused by resistant pathogens to ciprofloxacin 9. Subjects with body mass index of more than 30 kg/m2
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Musculoskeletal adverse events | — |
Secondary
| Measure | Time frame |
|---|---|
| Any adverse events other than musculoskeletal adverse events;clinical results and therapeutic response;microbiological results and therapeutic response | — |
Countries
Korea, Republic of
Contacts
Public ContactYanghyun Kim
Samsung Medical Center
Outcome results
None listed