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The dose effect of ephedrine on the onset time after cisatracurium

The dose effect of ephedrine on the onset time and intubating condition after cisatracurium

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CRIS
Registry ID
KCT0000587
Enrollment
156
Registered
2012-11-22
Start date
2012-10-26
Completion date
Unknown
Last updated
2019-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Procedure/Surgery : The endotracheal intubation is performed at 90 sec after cisatracurium 0.15 mg/kg following ephedrine 30, 70, 110 µg/kg or placebo before 30 sec, respectively, and evaluate the res

Sponsors

Hanyang University Seoul Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Train-of-four (TOF) monitoring at the adductor pollicis muscle on the supine position American Society of Anesthesiologists physical status 1-2

Exclusion criteria

Exclusion criteria: patients with neuromuscular blocking agents or neuromuscular disease patients with the history or family history of the allergy to neuromuscular blocking agents patients with cardiovascular diseases or hypertension patients with pregnancy or breastfeeding

Design outcomes

Primary

MeasureTime frame
response of endotracheal intubation

Secondary

MeasureTime frame
Blood pressure and heart rate ;train-of-four (TOF) ratio of adductor pollicis and bispectral index (BIS)

Countries

Korea, Republic of

Contacts

Public ContactDong Cha

Hanyang University Seoul Hospital

Outcome results

None listed

Source: CRIS (via WHO ICTRP) · Data processed: Feb 4, 2026