The effect of Palonosetron for the prevention of postoperative nausea and vomiting

The effect of Palonosetron for the prevention of postoperative nausea and vomiting in women patients using intravenous patient-controlled analgesia

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CRIS

Registry ID

KCT0000581

Enrollment

214

Registered

2012-11-14

Start date

2010-11-08

Completion date

Unknown

Last updated

2019-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Drug : Compared administration of palonosetron 0.075 mg plus dexamethasone 5 mg with dexamethasone 5 mg alone intravenoualy administered after anesthesia induction

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: Heathy, American Society of Anesiologists physical status Classification 1 or 2, women patient undergoing elective surgery under general anesthesia who received intravenous patient-controlled analgesia using fentanyl for postoperative pain control

Exclusion criteria

Exclusion criteria: 1. The patients who have Respiratory, cardiovascular, gastrointestinal, hepatic ,renal, or Psychological disease 2. Pregnant women, morbid obesity 3, The patient who had nausea and vomiting, or received antiemetics or steroid within 24 hours before surgery 4. The patient who can not communicate about pain assessment, or unable to use PCA 5, Addiction or abuse for opioids or drugs

Design outcomes

Primary

Measure	Time frame
Incidence of nausea and vomiting during 24 h after operation	—

Secondary

Measure	Time frame
Incidence of nausea and vomiting during 24-48 h after operation;Severity of nausea;Rescue antiemtics use;Adverse effects	—

Countries

Korea, Republic of

Contacts

Public ContactSoon Im Kim

Soon Chun Hyang University Hospital Seoul

Outcome results