The effect of intravenous magnesium sulfate on the consumption of epidural PCA

The effect of intravenous infusion of magnesium sulphate during abdominal operation by laparotomy on postoperative epidural analgesia

Status

Unknown

Phases

Phase 4

Study type

Interventional

Source

CRIS

Registry ID

KCT0000559

Enrollment

Registered

2012-10-15

Start date

2012-05-10

Completion date

Unknown

Last updated

2019-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Drug : In the experimental group, magnesium sulfate 50 mg/kg will be infused during 10 minutes and then, continuously infused at the rate of 15 mg/kg/hr. In control group, the same volume of normal sa

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: patients between 18 years and 65 years, American society of Anesthesiologist classification I-II undergoing open laparotomy

Exclusion criteria

Exclusion criteria: patient with hepatic,renal, pilmonary or cardiac dysfunction, Patient with neurologic disease, history of calcium channel blocker or magnesium, coagulopathy or history of anticoagulant, hypermagnesemia, history of allergy to magnesium, myasthesia gravia

Design outcomes

Secondary

Measure	Time frame
Serum magnesium level;the number of trial of epidural PCA;the severity of postoperative pain;the severity of postoperative nausea, vomitting and lower extremity weakness;the severity of postoperative lower extremity weakness	—

Primary

Measure	Time frame
The amount of used epidural PCA	—

Countries

Korea, Republic of

Contacts

Public ContactSeongjoo Park

Seoul National University Bundang Hospital

struka@snubh.org+82-31-787-7512

Outcome results