Palonosetron for the Prevention of PONV

The efficacy of palonosetron for the prevention of postoperative nausea and vomiting : a randomized double-blinded,placebo-controlled trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

CRIS

Registry ID

KCT0000537

Enrollment

204

Registered

2012-09-14

Start date

2010-12-01

Completion date

Unknown

Last updated

2019-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Drug : Palonosetron 0.075 mg IV or normal saline 1.5 ml IV

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: American Society of Anesthesiologists (ASA) physical status of ?-?,who were to undergo elective surgery under general anesthesia. The patient underwent laparoscopic cholecystectomy or laparoscopic herniorrhaphy, minor orthopedic surgery, minor plastic surgery, mastoidectomy and/or tympanoplasty, thyroidectomy, or tonsillectomy.

Exclusion criteria

Exclusion criteria: Pregnancy, body weight more than 30% above the ideal body weight, vomiting or retching within 24 h before the operation, administration of antiemetics or steroids within 24 h before the operation, or patients who electively requested an intravenous patient-controlled analgesia (IV PCA) using opioids for postoperative pain control or received an IV PCA using opioids postoperatively.

Design outcomes

Primary

Measure	Time frame
Incidence of PONV during 0-24 h postoperatively	—

Secondary

Measure	Time frame
Incidence of PONV during 24-72 h postoperatively; Severity of nausea; Use of rescue medication;Patient's satisfaction	—

Countries

Korea, Republic of

Contacts

Public ContactSoon Im Kim

Soon Chun Hyang University Hospital Seoul

Outcome results