Effects of Dexmedetomidine or Esmolol on the Concentration of Cytokines during Laparoscopic Cholecystectomy

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

CRIS

Registry ID

KCT0000503

Enrollment

100

Registered

2012-08-13

Start date

2011-01-26

Completion date

Unknown

Last updated

2019-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Drug : For the dexmedetomidine clinical dose group, dexmedetomidine is infused with a 1 ug/kg loading dose for 10minutes followed by infusion of maintenance dose 0.5 ug/kg/hr.For the dexmedetomidine s

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: laparoscopic cholecystectomy within 2hours chronic cholecystitis, gall bladder polyp, biliary colic American Society of Anesthesiologists physical status class 1 or 2

Exclusion criteria

Exclusion criteria: acute cholecystitis, gall bladder empyema underlying fever underlying leukocytosis diabetes mellitus, hypertension, coronary artery disease, arrhythmia etc difficult airway

Design outcomes

Primary

Measure	Time frame
plasma cytokine concentration	—

Secondary

Measure	Time frame
end tidal sevoflurane concentration;remifentanil concentration;mean arterial pressure;heart rate	—

Countries

Korea, Republic of

Contacts

Public ContactYongsuk Kim

The Catholic University of Korea, Seoul St. Mary's Hospital

Outcome results