Skip to content

The effects of palonoserton on postoperative nausea and vomiting(PONV) in total knee arthroplasty .

The effects of palonoserton on postoperative nausea and vomiting(PONV) in total knee arthroplasty.

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
CRIS
Registry ID
KCT0000485
Enrollment
120
Registered
2012-07-18
Start date
2012-02-16
Completion date
Unknown
Last updated
2019-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Drug : We randomly assinged into 2 groups, administering palonosetron0.075mg or no prophylaxis(placebo administration).In patients undergoing both knee arthroplasty, there was one-week interval betwee

Sponsors

Seoul National University Bundang Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients undergoing total knee arthroplasty who understands the study design and voluntarily agrees with the study.

Exclusion criteria

Exclusion criteria: Patients who are contraindicated to spinal anesthesia,did not administered iv-PCA or femoral nerve block, undergoing steroid therapy.

Design outcomes

Primary

MeasureTime frame
postoperative nausea and vomiting(PONV)

Secondary

MeasureTime frame
rescue antiemetics

Countries

Korea, Republic of

Contacts

Public ContactHye-min Sohn

Seoul National University Bundang Hospital

sophiesohn21@gmail.com+82-31-787-7499

Outcome results

None listed

Source: CRIS (via WHO ICTRP) · Data processed: Feb 4, 2026