Effects of low dose midazolam on bradycardia and sedation during dexmedetomidine infusion

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

CRIS

Registry ID

KCT0000467

Enrollment

Registered

2012-06-27

Start date

2012-06-21

Completion date

Unknown

Last updated

2019-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Drug : A. No premedication B. Standard vital monitoring: blood pressure, heart rate, oxygen saturation C. Spinal anesthesia D. Level check after spinal anesthesia and recheck vital signs E. Dexmedetom

4 = drowsy

3 = with eyes close, but responsive to verbal stimulation promptly

2 = with eyes close, only responsive to physical stimulation

and 1 = unresponsive to physical stimulation)

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients aged 20-60 yr with American Society of Anesthesiologists (ASA) status of I-II undergoing elective surgery under spinal anesthesia were included in this study

Exclusion criteria

Exclusion criteria: Patients with bradycardia (baseline heart rate < 50 beats min-1), third degree heart block, those taking ß-blockers, those who refused sedation during surgery, and those with AST, ALT, BUN, Cr levels not within the normal range were excluded.

Design outcomes

Primary

Measure	Time frame
Bradycardia (heart rate)	—

Secondary

Measure	Time frame
Observer’s Assessment of Alertness/Sedation Scale (OAA/S)	—

Countries

Korea, Republic of

Contacts

Public ContactDuk-Hee Chun

Bundang CHA General Hospital

leah1013@chamc.co.kr+82-31-780-5643

Outcome results