Validation of skin test before cephalosporin administration

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

CRIS

Registry ID

KCT0000455

Enrollment

1500

Registered

2012-06-07

Start date

2010-11-04

Completion date

Unknown

Last updated

2019-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Procedure/Surgery : To determine cephalosporin allergy, we prospectively conducted intradermal skin test with selected 1st, 2nd, and 3rd generation cephalosporins: ceftazol, cefotetan or cefamandol, c

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients who needed the use of preoperative cephalosporins.

Exclusion criteria

Exclusion criteria: Patients who have history of allergic reaction to beta lactam antibiotics previously or any skin disease including dermographism, antihistamine user and pregnant women were excluded from this study.

Design outcomes

Primary

Measure	Time frame
The sensitivity of cephalosporin skin test. ;The specificity of cephalosporin skin test. ;The positive predictive value (PPV) of cephalosporin skin test. ;The negative predictive value (NPV) of cephalosporin skin test.	—

Secondary

Measure	Time frame
The prevalence rate of immediated hypersensitivity to cephalosporins.;The cross-reactivity with penicillin and cephalosporins.	—

Countries

Korea, Republic of

Contacts

Public ContactSun-Young Yoon

Asan Medical Center

Outcome results