None listed
Conditions
Interventions
Radiation : The HCC patients with size =5 cm and 3 cm apart from gastrointestinal tract will be included in this study. Total stereotactic ablative radiotherapy (SABR) doses will be 60 Gy in 3 fractio
Sponsors
Korea Institute of Radiological & Medical Sciences
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Male or female patients =18 years of age 2. Intitially diagnosed or recurrent hepatocellular carcinoma (HCC) 3. Unresectable HCC 4. Cirrhotic status of Child Pugh class A or B7 5. Eastern Cooerative Oncology Group performance status 0 or 1 6. single or sum of multiple tumor =5 cm 7. HCC with 3 cm apart from gastrointestinal tract 8. The volume of uninvolved must be at least 1000 ml 9. Incomplete response after trans-arterial chemo-embolization of 1-5 10. A single lesion or multiple lesions including portal vein tumor thrombosis included in radiation field with one or consecutive sesseions of SBRT 11. No evidence of an uncontrolled lesion at any other site 12. No evidence of complications of liver cirrhosis 13. No evidence of uncontrolled inter-current illness 14. Patient or gaurdian must be able to provide verbal and written informed consent
Exclusion criteria
Exclusion criteria: 1. Patient with previous history of abdominal radiation 2. Direc invasion to esophagus, stomach or colon by HCC
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Local control rate | — |
Secondary
| Measure | Time frame |
|---|---|
| Overall survival rate;Progression free survival rate;Intrahepatic recurrence free survival rate;treatment related toxicity | — |
Countries
Korea, Republic of
Contacts
Public ContactSun Hyun Bae
Korea Institute of Radiological & Medical Sciences
Outcome results
None listed