None listed
Conditions
Interventions
Dietary Supplement : Thirty patients fulfilling Rome III criteria for functional constipation and 30 controls were enrolled. Fecal samples were obtained before and after taking VSL#3 powder (450 billi
Sponsors
Ewha Womans University Medical Center
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1)20-60 year old patients 2)patients fulfilling Rome III criteria for functional constipation and their age- and sex-matched controls
Exclusion criteria
Exclusion criteria: 1) pregnant or breastfeeding women 2) organic bowel disease 3) diagnosed with advanced adenoma within 3 years 4) irritable bowel disease(Rome III) 5) OP history of bowel surgery or cholecystectomy 6) lactose malabsorption 7) DM or severe medical disease(heart and lung, liver and kidney, malignancy, immunocompromised patients) 8)Heavy alcoholics 9)difficult to Cooperate 10) antibiotics, probiotics, or synbiotics within 1 month.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| difference of gut microbiome between functional constipation and control, and the influences of a probiotic , VSL#3 on the microflora of each group | — |
Secondary
| Measure | Time frame |
|---|---|
| Influence of probiotics on bowel symptom of constipation patients | — |
Countries
Korea, Republic of
Contacts
Public ContactSeong-Eun Kim
Ewha Womans University Medical Center
Outcome results
None listed