Could hemodynamic stability block the increasing of Endothelin-1 levels during carbon dioxide pneumoperitoneum?

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

CRIS

Registry ID

KCT0000442

Enrollment

Registered

2012-05-15

Start date

2012-01-09

Completion date

Unknown

Last updated

2019-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Procedure/Surgery : Stroke volume variance was continuously monitored by using Edwards FloTrac System (Edwards Lifesciences, Irvine, CA) and maintained within 10% variation. During surgery, heart rate

Eligibility

Sex/Gender

Male

Inclusion criteria

Inclusion criteria: Patients who were American Society of Anesthesiologists (ASA) physical status class I or II and who were scheduled to undergo robot assisted laparoscopic prostatectomy under general anaesthesia were recruited for this study.

Exclusion criteria

Exclusion criteria: Patients with a history of severe respiratory disease, cardiac disease, hepatic dysfunction, renal impairment, or coagulopathy, and those with a history of medication which affect ADH secretion or action, such as, antihypertensive drugs, diuretics, monoamine oxidase inhibitors, non-steroidal anti-inflammatory drugs, and anticonvulsants were excluded.

Design outcomes

Primary

Measure	Time frame
endothelin-1	—

Secondary

Measure	Time frame
Catecholamine( norepinephrine, epinephrine);vasopressin	—

Countries

Korea, Republic of

Contacts

Public ContactChoon-Hak Lim

Korea University Anam Hospital

Outcome results