Effect of Lactobacillus gasseri BNR17 on glucose tolerance (Pilot study)

Effect of Lactobacillus gasseri BNR17 isolated from human breast milk on glucose tolerance(Pilot study)

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

CRIS

Registry ID

KCT0000368

Enrollment

Registered

2012-02-24

Start date

2012-02-06

Completion date

Unknown

Last updated

2019-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Dietary Supplement : Consumption of Lactobacillus gasseri BNR17(low, medium or high dose) or placebo for 4 weeks(twice a day)

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) Voluntarily agree to participate and sign in informed consent form 2) Adults over 20 ages 3) BMI: = 23kg/m2 4) Blood glucose level at 30 minutes after oral glucose loading = 140mg/dl 5) A subjective symptom of irritable bowel syndrome

Exclusion criteria

Exclusion criteria: 1) Continuous consumption of dietary supplement or oriental medicine within 4 weeks before the first visit 2) Inflammatory disease or current consumption of insulin, antiinflammatory analgesic drug, antibiotic, anticoagulant, ACE inhibitor, angiotensin ?antagonist 3) Participation in other human study within 30days before the first visit 4) Pregnant or lactating women 5) Alcoholic 6) Following diseases : Heart failure, Coronary artery disease, Uncontrolled hypertension, Liver dysfunction, Renal dysfunction, Malignant tumors , Mental disease 7) Hypersensitivity to probiotics 8) Any condition that the principal investigator believes may put the subjects at undue risk

Design outcomes

Primary

Measure	Time frame
Oral glucose tolerance test	—

Secondary

Measure	Time frame
Lactobacillus gasseri BNR17 concentration in feces;Interleukin-10 level in feces ;Bowel movement habit and satiety questionnaire	—

Countries

Korea, Republic of

Contacts

Public ContactJiyeon Kim

Ewha Womans University

Outcome results