None listed
Conditions
Interventions
Dietary Supplement : Subjects will be randomly assigned to receive Poly-?-glutamic acid(?-PGA) 0.15g or placebo. Subjets will orally self-adminster Poly-?-glutamic acid(?-PGA) 0.15g or placebo qd, for
Sponsors
Inje University Seoul Paik Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Male and female subjects of 200mg/dl -500mg/dl in serum triglycerides 2) Male and female subjects between 19-65 years old 3) Evidense of a personally signed and dated informed consent document indicating that the subject has been informed of all pertinent aspects of the trial.
Exclusion criteria
Exclusion criteria: 1. Subjects who took a drug(total-cholesterol treatment) within 3 months 2. Subjects with hyperlipidemia who need a drug treatment 3. Subjects with cardiovascular disorder 4. Subjects who use of antiobestic drug 5. Subjects who use of beta blocker or hydragogue 6. Subjects with diabetes (fasting blood glucose 126= or random blood glucose =200, and also use of hypoglycemic agent or insulin) 7. Subjects with endocrinopathy or abnormal screening TSH value(=0.1uU/ml or =10uU/ml) 8. Subjects with serum AST/ALT = 3 times the upper limit of normal 9. Subjects with severe gastrointestinal symptom(heartburn, indigestion) 10. Subjects who drinks alcohol 4 times per a week 11. Subjects with disease of gallbladder, gastrointestinal, gout, porphyria 12. Subjects with a history of CNS disorder(depressivedisorder,schizophrenia, alcoholism, drug addiction ) 13. Subjects with malnutrition 14. Woman who are pregnant or lactating 15. Subjects who have a plan to participate in other clinical trial 16. Subjects who took part in other clinical trial within 3 months 17. Subjects which in the opinion investigator could affect preclude evauation of response
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Serum triglyceride | — |
Secondary
| Measure | Time frame |
|---|---|
| Weight;BMI(Body mass index);Serum Total-cholesterol | — |
Countries
Korea, Republic of
Contacts
Public ContactYangim Hur
Inje University Seoul Paik Hospital
Outcome results
None listed