Comparison of palonosetron with ondansetron for prevention of postoperative and postdischarge nausea and vomiting

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

CRIS

Registry ID

KCT0000336

Enrollment

150

Registered

2012-02-02

Start date

2012-01-12

Completion date

Unknown

Last updated

2019-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Drug : Patients were divided into two groups: the palanosetron group (0.075 mg i.v.

n=75) and the ondansetron group (8 mg i.v.

n=75 ) The treatments were given before the end of surgery. It was a double blind study (patients and a investigator.)

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: female healthy patients, aged 19-65 years, undergoing elective pelviscopic gynaecological surgery or brest operation, American Society of Anesthesiologists (ASA) classes 1-2, confirmed consent.

Exclusion criteria

Exclusion criteria: pregnancy, user of antiemetics for treating chronic nausea/vomiting or retching within 24 h before the operation, administration of antiemetics or steroids or psychoactive medications within 24 h before the operation, and respiratory, cardiovascular, renal, hepatic, endocrine, gastrointestinal, or neurological disease. hypersensitivity or anaphylaxis, chronic opioid user

Design outcomes

Primary

Measure	Time frame
Nausea;retching;vomiting	—

Secondary

Measure	Time frame
Amount of antiemetics.;complete response ;Pain score and amount of rescue analegics.;Satisfaction score	—

Countries

Korea, Republic of

Contacts

Public ContactJung Ryu

Seoul National University Bundang Hospital

Ryejh@snubh.org+82-31-787-7499

Outcome results