None listed
Conditions
Interventions
Behavioral : Both groups will be provided low-calory, low-fat and low-sodium diet education and nutrition education materials at 0 week and 12week.
Additionally, rice-based diet group will be educate
Sponsors
Inje University Seoul Paik Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: ? any 3 of 5 constitute diagnosis of metabolic syndrome 1. Elevated waist circumference : =90 cm in men =85 cm in women 2. Elevated triglycerides : =150 mg/dL (1.7 mmol/L) or On drug treatment for elevated triglycerides 3. Reduced HDL-C : <40 mg/dL (1.03 mmol/L) in men <50 mg/dL (1.3 mmol/L) in women or On drug treatment for reduced HDL-C‡ 4. Elevated blood pressure: =130 mm Hg systolic blood pressure or =85 mm Hg diastolic blood pressure or On antihypertensive drug treatment in a patient with a history of hypertension 5. Elevated fasting glucose : =100 mg/dL or On drug treatment for elevated glucose ? Patients who agreed to write about food diary and physical activity Questionnaire ? Patients who agreed to participate volutary in this clinical trial
Exclusion criteria
Exclusion criteria: ? The patients with physical measurements are difficult due to anatomical change, such as surgical resection of part of the body ? The Patients with thyroid fuction disease (TSH is under 0.1 uU/ml, or over 10 uU/ml) ? The Patients with severe cerebrovascular disease(infarct, hemorrage), cardiac disease(angina, myocardiac infarct, heart failure, arrhythmias that require treatment) within recent 6 months. (If that patient's clinical status is stable, they can participate in the clinical trial according to investgator) ? The Patients with severe liver or kidney function abnormality - plasma ALT or AST level is more than 3 times the upper limit of normal - plsma creatinine level is more than 1.5 times the upper limit of normal ? The Patients with mental illness such as depression, Schizophrenia, alcoholism, drug addiction etc. ? Pregnant and lactating women, and women of childbearing age who do not agree with choose an appropriate contraceptive method or are planning to pregnant ? The patient who take the medicine that can affect the state of weight, glucose and lipid level (uptake inhibitors, antidepressant, appetite suppressant, antiobesity-related health functional food / supplements, antipsychotics, contraceptives, steroid, and hormon)within recent 3 months ? The patients who had surgical procedure for reducing weight (bariatric surgery such as gastric bypass and gastric banding) ? The patients who lose weignt over 10 percent within 3 months ? The patients who took part in other clinical trial within 3 months ? The patients who cannot excersise due to severe musculoskeletal disorders ? The patients who stopped smoking within recent 6 months or chage frequently smoking habit ? The patients who have low motivation for attending or will not following the observances of this clinical trial, depend on opinion of representative clinical trials
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| weight ;waist circumference;triglyceride ;HDL-cholesterol;fasting glucose;blood pressure | — |
Secondary
| Measure | Time frame |
|---|---|
| body mass index;hip circumference;fat maas, free fat mass;total-cholesterol;insulin;highly sensitive C-reactive protein(hsCRP);calory of each diet;Nutrients of each diet;LDL-cholesterol | — |
Countries
Korea, Republic of
Contacts
Public ContactYang Hur
Inje University Seoul Paik Hospital
Outcome results
None listed