The prospective trial for the usefulness of hepatic vein arrival time using a microbubble contrast enhanced ultrasonography in non-invasive estimation of the severity of portal hypertension in cirrhotic patients

The usefulness of hepatic vein arrival time using a microbubble contrast enhanced ultrasonography in non-invasive estimation of the severity of portal hypertension in cirrhotic patients

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

CRIS

Registry ID

KCT0000257

Enrollment

105

Registered

2011-11-03

Start date

2011-05-10

Completion date

Unknown

Last updated

2019-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Procedure/Surgery : The measurement of hepatic venous pressure gradient (HVPG) and Hepatic vein arrival time (HVAT) using a microbubble contrast enhanced ultrasonography (CEUS)are evaluated. In this s

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: (1) Clinically definite liver cirrhosis patients or confirmed by liver biopsy (2) Patients who evaluate portal hypertension by hepatic vein pressure gradient (3) Patients who agree with enroll this study

Exclusion criteria

Exclusion criteria: (1) Baseline systolic blood pressure10mg/dL) (6) Serum creatinine = 1.2mg/dL (7) Past history of shunt procedure or TIPS (8) Administration of beta-blocker, ACE inhibitor, nitrate within 1month (9) Pregnancy (10) Patients who disagree with enroll this study (11) Patients who did not perform this study

Design outcomes

Primary

Measure	Time frame
The relationship between HAVT and HVPG	—

Secondary

Measure	Time frame
The mortality and variceal bleeding during 3years follow up;The variceal bleeding during 3years follow up	—

Countries

Korea, Republic of

Contacts

Public ContactMoon Kim

Yonsei University, Wonju Severance Christian Hospital

Outcome results