Influence of atropine-induced vagal modulation on dynamic cerebral autoregulation in healthy volunteers

Influence of vagal modulation on dynamic cerebral autoregulation in healthy volunteers

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

CRIS

Registry ID

KCT0000211

Enrollment

Registered

2011-10-27

Start date

2010-07-24

Completion date

Unknown

Last updated

2019-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Drug : This study was a randomized, double-blind, cross-over comparison among the vagotonic 2 ?/? atropine, vagolytic 10 ?/? atropine, and placebo (an equal volume of normal saline) groups. At least

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: healthy volunteers

Exclusion criteria

Exclusion criteria: drug user for any disease hypertension smoker consuming caffeinated or alcoholic beverages at least 24 h prior to study.

Design outcomes

Primary

Measure	Time frame
autoregulatory response	—

Secondary

Measure	Time frame
transfer function coherence;spectral poser analysis of cerebral blood flow velocity;spectral poser analysis of heart rate;spectral poser analysis of blood pressure;transfer function phase;transfer function gain	—

Countries

Korea, Republic of

Contacts

Public ContactWoo-Jong Choi

Asan Medical Center

Outcome results