Effect of exogenous albumin on the incidence of postoperative acute kidney injury in patients with hypoalbuminemia undergoing off-pump coronary bypass surgery

Effect of exogenous albumin on the incidence of postoperative acute kidney injury in patients with preoperative albumin level < 4.0g/dl undergoing off-pump coronary bypass surgery

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

CRIS

Registry ID

KCT0000210

Enrollment

220

Registered

2011-10-27

Start date

2011-09-15

Completion date

Unknown

Last updated

2019-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Drug : 220 consecutive patients undergoing elective OPCAB and showing an serum albumin level of < 4.0 g/dL the day before surgery were included. The patients were prospectively randomized (closed enve

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: patients above 20 years of age and of either sex undergoing elective off pump coronary artery bypass surgery and showing an serum albumin level of < 4.0 g/dL the day before surgery

Exclusion criteria

Exclusion criteria: 1) emergency 2) patients with a history of allergic reactions to human albumin 3) patients with preoperative creatinine level = 1.5 mg/dl, or requiring dialysis 4) patients with a preoperative inotrope, intraaortic balloon pump, or ventricular assist device support 5) left ventricular ejection fraction (LVEF) = 40% 6) patients undergoing concomitant valvular or aortic surgery

Design outcomes

Primary

Measure	Time frame
Incidence of acute kidney injury after surgery	—

Secondary

Measure	Time frame
time to eligibility for discharge from intensive care unit;time to eligibility for discharge from hospital;incidence of renal replacement therapy after surgery;death from any cause within 30 days of surgery	—

Countries

Korea, Republic of

Contacts

Public ContactEun Ho Lee

Asan Medical Center

leho@naver.com+82-2-3010-3888

Outcome results