Efficacy of ramosetron and palonosetron on patient-controlled analgesia related postoperative nausea and vomiting in gynecological laparoscopic surgery -randomised controlled trial-

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CRIS

Registry ID

KCT0000183

Enrollment

320

Registered

2011-09-08

Start date

2011-07-08

Completion date

Unknown

Last updated

2019-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Procedure/Surgery : C group: Normal saline 50 ml was administered for 10 minutes at the end of surgery. R group: Ramosetron 0.3 mg was mixed in normal saline 50 ml and administered for 10 minutes at

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: Patients undergoing gynaecologic laparoscopic surgery with intravenous PCA for postoperative pain control were enrolled. The patients were American Society of Anesthesiologists Patient Status (ASA PS) I or II, and at least 18 years old.

Exclusion criteria

Exclusion criteria: Patients were excluded if the following criteria present: 1) urgent or emergent case, 2) re-do case, 3) allergy to egg or soybean oil, 4) history of drug abuse, 5) receiving current medications, 6) concurrent other surgery, 7) surgery within 1 hour and 8) discharge within 72 hours.

Design outcomes

Primary

Measure	Time frame
postoperative nausea and vomiting	—

Secondary

Measure	Time frame
postoperative pain	—

Countries

Korea, Republic of

Contacts

Public ContactWoon-Seok Kang

Konkuk University

Outcome results