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Effect of positive end-expiratory pressure on left ventricular diastolic function in patients with pre-existing diastolic dysfunction among patients undergoing off-pump coronary artery bypass graft surgery

Effect of positive end-expiratory pressure on left ventricular diastolic function in patients with pre-existing diastolic dysfunction among patients undergoing off-pump coronary artery bypass graft surgery

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CRIS
Registry ID
KCT0000090
Enrollment
17
Registered
2011-01-27
Start date
2011-01-19
Completion date
Unknown
Last updated
2019-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Others : First measurements of echocardiogaphic and hemodynamic variables were performed at baseline with 0 cmH2O PEEP and after stepwise increase of PEEP levels: second were performed at the end of 1

Sponsors

Asan Medical Center
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients were included in the study if they showed normal sinus rhythm on preoperative electrocardiogram and preoperative ejection fraction > 50% with normal left ventricular basal lateral segment wall motion on preoperative echocardiographic evaluation

Exclusion criteria

Exclusion criteria: Exclusion criteria were age < 18, combined valvular heart disease or peak early diastolic velocity of lateral mitral annuls (E') = 8.5 cm/s at immediately after anesthetic induction.

Design outcomes

Primary

MeasureTime frame
peak early diastolic velocity of lateral mitral annuls (E')—

Secondary

MeasureTime frame
peak systolic velocity of lateral mitral annulus (S')—

Countries

Korea, Republic of

Contacts

Public ContactJi-Hyun Chin

Asan Medical Center

Outcome results

None listed

Source: CRIS (via WHO ICTRP) · Data processed: Feb 4, 2026