Impact of Intravenous Lidocaine on Myocardial Injury after Off Pump Coronary Artery Surgery

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

CRIS

Registry ID

KCT0000023

Enrollment

106

Registered

2010-08-25

Start date

2010-08-02

Completion date

Unknown

Last updated

2019-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Drug : Just after induction of anaesthesia, patients assigned to receive lidocaine were given an intravenous bolus injection of 1.5 mg kg-1 lidocaine followed by a continuous i.v. infusion of 2 mg kg-

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: patients aged 18 to 80 yr undergoing elective OPCAB under general anaesthesia

Exclusion criteria

Exclusion criteria: contraindications for lidocaine or opioid use, pulmonary or hepatic diseases, psychiatric disorders, recent (1.3 mg dl-1) before surgery, left ventricular ejection fraction (LVEF) <50%, and patients undergoing emergency or repeat operations, or concomitant valvular or aortic surgery.

Design outcomes

Primary

Measure	Time frame
TnI and CK-MB concentrations	—

Secondary

Measure	Time frame
postoperative major adverse events	—

Countries

Korea, Republic of

Contacts

Public ContactEun-Ho Lee

Asan Medical Center

Outcome results