The sparing effects of low-dose esmolol on inhalation anesthetics during laparoscopic gynecologic surgery

Prospective, randomized, two-arm parallel group trial for the sparing effects of low-dose esmolol on inhalation anesthetics in patients undergoing laparoscopic gynecologic surgery

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

CRIS

Registry ID

KCT0000005

Enrollment

Registered

2010-06-23

Start date

2009-12-21

Completion date

Unknown

Last updated

2019-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Drug : The treatment group (n = 27) is infused with a loading dose of 0.5 mg/kg esmolol, followed by an infusion of 30 &micro

g/kg/min during surgery. The control group (n = 27) is infused with the same volume of normal saline.

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: The women who are aged between 20 and 60 years with an American Society of Anesthesiology status of I or II and scheduled for elective laparoscopic gynaecologic surgery for 2 hour general anaesthesia

Exclusion criteria

Exclusion criteria: Patients who have cardiovascular diseases, such as hypertension, arrhythmias, or myocardial ischaemia, are haemodynamically unstable (i.e., bleeding, hypovolaemia, or loss of body fluid), or have asthma or chronic obstructive pulmonary disease, allergies to the study drug, or a body mass index under 16 or over 30 kg/m2.

Design outcomes

Primary

Measure	Time frame
The difference between the input concentration before infusing the study drug and the input concentration after infusing the study drug	—

Secondary

Measure	Time frame
pain degree after surgery;analgesic requirement after surgery	—

Countries

Korea, Republic of

Contacts

Public ContactYoung Eun Moon

The Catholic University of Korea, Seoul St. Mary's Hospital

Outcome results