Skip to content

Effectiveness and safety of GBR with an open barrier membrane technique using PTFE

Effectiveness and safety of guided bone regeneration (GBR) with an open barrier membrane technique using polytetrafluoroethylene

Status
Recruiting
Phases
Phase 1
Study type
Interventional
Source
JPRN
Registry ID
JPRN-jRCTs072250025
Enrollment
20
Registered
2025-05-22
Start date
2025-06-03
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Missing teeth guided bone regeneration

Interventions

None listed

Sponsors

Odatsu Tetsuro
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Patients who recive dental implant treatment 2. Patients aged 18 to 90 at the time of registration 3. Patients who have loss of molar tooth and planned guided bone regeneration 4. Patients who are unable to place implants and bone aubumentation simultaneously 5. Patients have provided written consent of their own free will to particitape

Exclusion criteria

Exclusion criteria: 1. Patients who need the vertical bone augumentation 2. Patients with acute inflammation at the treatment site 3. Patients with lacking the ability to make decision 4. Patients with drug allergies 5. Pregnant women, patients who may be pregnant, or patients who are breastfeeding 6. Patients participating in clinical trials or other clinical research 7. Patients with uncontrolled metabolic diseases 8. Patients who are taking long-term steroids or immunosuppressants for autoimmune diseases 9. Patients taking bone resorption inhibitors 10. Patients undergoing radiation therapy 11. Patients who are currently smoking 12. Other patients deemed inappropriate by the principal investigator or subinvestigator

Design outcomes

Primary

MeasureTime frame
Absorption rate about 5 months after GBR compared with after surgery by CBCT analysis Safety assessment

Secondary

MeasureTime frame
Area of attachment gingiva New bone formation measured by histology

Contacts

Public ContactTetsuro Odatsu

Nagasaki University Hospital

odatsu@nagasaki-u.ac.jp+81-95-819-7686

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026