Efficacy of HFNC Respiratory Management to Post-extubation Acute Pulmonary Recruitment in Oral Surgery Patients

Efficacy of High Flow Nasal Cannula Respiratory Management Applied to Post-extubation Acute Pulmonary Recruitment in Oral Surgery Patients - Efficacy of HFNC Respiratory Management Applied to Post-extubation Acute Pulmonary Recruitment in Oral Surgery Patients

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-jRCTs072240111

Enrollment

Registered

2025-02-14

Start date

2025-02-14

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Oral disease

Interventions

After extubation, study subjects will be randomly assigned to receive HFNC respiratory management using AIRVO3(HFNC group) or oxygen therapy using a nasal cannula (nasal cannula group). Postoperative

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: (i) Patients undergoing oral surgery under general anesthesia with a scheduled application surgery time of 4-5 hours. (ii) Patients undergoing respiratory management with oxygen administration during the acute postoperative period (3 to 5 hours) until they are released after returning to the general ward. (iii) Patients whose age is between 18 and 85 years old at the time of obtaining consent. (iv) Patients who have received a thorough explanation of their participation in this study, and who have given written consent of their own free will based on sufficient understanding.

Exclusion criteria

Exclusion criteria: (i) Patients already receiving continuous oxygen administration via nasal cannula (home oxygen therapy) (ii) Patients who cannot breathe through the nose (iii) Patients who cannot reduce or discontinue antithrombotic drugs after surgery (iv) Patients with a history of pneumothorax (v) Patients with significant postoperative morphological changes such as extensive resection of the jawbone (vi) Patients participating in clinical trials or other clinical studies (vii) Patients who are deemed inappropriate as research subjects by the principal investigator.

Design outcomes

Primary

Measure	Time frame
Evaluation by electrical chest tomography with EIT 1) Effect of PEEP augmentation: global delta EELZ, ventral delta EELZ, dorsal delta EELZ, GI index 2) Improvement of respiratory workload: Delta Z, total tidal volume (TV), ventral TV, dorsal TV, minute minute ventilation rate, corrected minute ventilation rate (= minute ventilation rate x PaCO2/40)	—

Secondary

Measure	Time frame
ROX index	—

Contacts

Public ContactTakao Ayuse

Nagasaki University Hospital

ayuse@nagasaki-u.ac.jp+81-958197713

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026