Respiratory faiure
Conditions
Interventions
Patients who are on the verge of ventilator withdrawal after at least 48 hours of ventilatory management in the intensive care unit will be the study subjects, and HFNC will be used to evaluate the ef
Sponsors
Araki Hiroshi
Fisher & Paykel Healthcare Limited
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: (1)Patients admitted to the Intensive Care Unit of Nagasaki University Hospital and under ventilatory management by an intensivist for 48 hours or longer (2)Patients who are on schedule to be weaned off the mechanical ventilator (3)Patients who meet the criteria for weaning from the mechanica ventilator (see below) (4)Age: Adult patients who are at least 18 years old at the time of consent (5)Gender: Any gender (6)Patients who have been fully informed about their participation in this study, and who have given written consent of their own free will or that of their family members based on a thorough understanding of the study.
Exclusion criteria
Exclusion criteria: (1) Patients who cannot breathe through the nose (2) Pregnant patients (3) Patients who do not agree to participate in the study (4) Other patients deemed inappropriate as research subjects by the principal investigator Criteria for weaning from ventilator Spontaneous respiration mode Pressure support pressure less than 5cmH20 End-Expiratory positive pressure less than 5cmH2O With the above setting Respiration frequency below 25 breaths per minutes Ventilatory volume per breath over 6mL per predicted body weight Arterial blood partial pressure of carbon dioxide below 250mmHg After completion of sedation, patients opens eyes on verbal instruction, able to follow simple instruction, RASS score is between -1 to 0, no new arrhythmias, no excessive use of respiratory assist muscles, no seesaw breathing
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Compliance with AIRVO3 | — |
Secondary
| Measure | Time frame |
|---|---|
| (1) Mean respiratory rate (2) Mean value of transcutaneous oxygen saturation (3) Average value of administered FIO2 (4) Average value of administered flow rate (5) Average value of temperature of heating and humidification (6) Nasal cannula size (7) ROX index (transcutaneous oxygen saturation/FIO2/respiration rate) | — |
Contacts
Public ContactHiroshi Araki
Nagasaki University Hospital
Outcome results
None listed