Comparative study of the safety and efficacy of the bio-degradable membranes for guided bone regeneration

Evaluation of the safety and efficacy of the bio-degradable membrane made of L-lactide/e- caprolactone co-polymers for guided bone regeneration: comparative study with collagen membrane

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

JPRN

Registry ID

JPRN-jRCTs072200063

Enrollment

Registered

2020-12-09

Start date

2021-02-03

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Alveolar bone atrophy

Interventions

Bone biopsy is performed for category 3 subjects

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Patients who require alveolar ridge augmentation with GBR for oral rehabilitation using dental implants 2. 20 plus and under 90 years old 3. Patients who make written informed consent.

Exclusion criteria

Exclusion criteria: 1. Patients who have sever blood diseases 2. Patients who have calcium metabolic diseases, or immune system abnormalities. 3. Patients who are difficult to be followed up 4. .Patients who are restricted to comply the requirements of this study. 5. Smokers 6. Patients who needs the legal representative. 7. Partients who are judged to be inappropriate to participate the study by the principal or cooperative doctors.

Design outcomes

Primary

Measure	Time frame
Efficacy: Amount of bone formation evaluated by CT analysis	—

Secondary

Measure	Time frame
Safety and Efficacy evaluated by ISQ value of dental implants and histrogical evalusation with bone biopsy	—

Contacts

Public ContactSeigo Ohba

Nagasaki University Hospital

sohba@nagasaki-u.ac.jp+81-95-819-7704

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026