COPD
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: The severity of COPD is moderate (GOLD2) or more. Age: At the time of obtaining consent, an adult patient 40 years or older Gender: Any Hospitalization / Outpatient: Outpatient only Patients who have been given sufficient explanations to participate in this study and have given their full understanding and informed consent from the patient
Exclusion criteria
Exclusion criteria: Patients who cannot breathe nose Patients with a history of pneumothorax Patients with active malignancy Patients with acute disease (such as acute myocardial infarction) Patients currently diagnosed with asthma (Patients who have a history of asthma but are currently diagnosed with COPD are eligible for inclusion.) Patients who have been diagnosed with obstructive sleep apnea in the past and who are strongly suspected clinically Patients already using NHF Patients who are using non-invasive ventilation (NIV) at night Patients with severe disease of the kidney, liver or circulatory system Patients who are considered inappropriate by the Principal Investigator Patients who are positive for the new coronavirus (SARS-CoV-2) PCR test
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Rate of expiratory phase after swallowing saliva | — |
Secondary
| Measure | Time frame |
|---|---|
| 1) Time-weighted average value of tcpO2 (average partial pressure during observation period) 2) Time-weighted average value of tcpCO2 (average partial pressure during observation period) 3) Time-weighted average value of SpO2 (average oxygen saturation during observation period) 4) Time-weighted average respiratory rate (average respiratory rate during the observation period) | — |
Contacts
Nagasaki University Hospital