Prevention of radiation induced dental caries by topical fluoride with tray

Multicenter study of effects of topical fluoride application with tray on prevention of dental caries in patients undergoing head and neck radiotherapy

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

JPRN

Registry ID

JPRN-jRCTs072190039

Enrollment

Registered

2020-01-07

Start date

2020-07-13

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Head and neck cancer head and neck cancer, radiation-induced dental caries

Interventions

Custom tray with tooth paste containing 1450 ppm fluoride is attached at bedtime everyday for one year.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients with head and neck cancer undergoing chemo-radiotherapy

Exclusion criteria

Exclusion criteria: Patients with problem in judgement

Design outcomes

Primary

Measure	Time frame
Prevention of radiation-induced dental caries	—

Secondary

Measure	Time frame
Investigation of factors related to development of radiation induced dental caries	—

Contacts

Public ContactSakiko Soutome

Nagasaki University Hospital

sakiko@nagasaki-u.ac.jp+81-95-819-7663

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026