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Study on prevention of hypercapnia by Nasal High Flow in patients undergoing endoscopic retrograde cholangiopancreatography during intravenous anesthesia

Study on prevention of hypercapnia by Nasal High Flow in patients undergoing endoscopic retrograde cholangiopancreatography during intravenous anesthesia

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-jRCTs072190021
Enrollment
80
Registered
2019-08-26
Start date
2020-01-14
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Biliary disease

Interventions

Sponsors

Ayuse Takao
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1) Age: Adult patients whose age is between 20 and 85 years old at the time of obtaining consent 2) Gender: Any question 3) Hospitalization / outpatient: hospitalization only 4) Patients who have received sufficient explanation for participation in this study, and who have received sufficient written consent from the patient himself / herself with sufficient understanding.

Exclusion criteria

Exclusion criteria: 1) Continuous administration of oxygen by nasal cannula (home oxygen therapy) 2) Patients who cannot breathe nose 3) Patients who cannot reduce or discontinue antithrombotic drugs on the day before the endoscope 4) Patients with a history of pneumothorax 5) Other patients who are determined to be inappropriate as research subjects by the principal investigator 6) Patients who are positive for the new coronavirus (SARS-CoV-2) PCR test

Design outcomes

Primary

MeasureTime frame
1) Occurrence of marked hypercarbonemia showing maximum value of percutaneous carbon dioxide concentration over 60 mmHg (equivalent to PaCO2> 55 mmHg) during intravenous anesthesia 2) Area under curve (AUC) of percutaneous carbon dioxide concentration per unit time at intravenous anesthesia 3) Duration of moderate hypercarbonemia showing maximum value of 50mmHg or more (equivalent to PaCO2> 45mmHg) during percutaneous anesthesia with intravenous anesthesia 4) Occurrence of hypoxemia showing 90% or less of the value of percutaneous oxygen saturation during intravenous anesthesia

Secondary

MeasureTime frame
1) Anesthesia depth assessment (Ramsay scale) 2) Anesthesia dose

Contacts

Public ContactTakao Ayuse

Nagasaki University Hospital

ayuse@nagasaki-u.ac.jp+81-95-819-7713

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026