Biliary disease
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1) Age: Adult patients whose age is between 20 and 85 years old at the time of obtaining consent 2) Gender: Any question 3) Hospitalization / outpatient: hospitalization only 4) Patients who have received sufficient explanation for participation in this study, and who have received sufficient written consent from the patient himself / herself with sufficient understanding.
Exclusion criteria
Exclusion criteria: 1) Continuous administration of oxygen by nasal cannula (home oxygen therapy) 2) Patients who cannot breathe nose 3) Patients who cannot reduce or discontinue antithrombotic drugs on the day before the endoscope 4) Patients with a history of pneumothorax 5) Other patients who are determined to be inappropriate as research subjects by the principal investigator 6) Patients who are positive for the new coronavirus (SARS-CoV-2) PCR test
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1) Occurrence of marked hypercarbonemia showing maximum value of percutaneous carbon dioxide concentration over 60 mmHg (equivalent to PaCO2> 55 mmHg) during intravenous anesthesia 2) Area under curve (AUC) of percutaneous carbon dioxide concentration per unit time at intravenous anesthesia 3) Duration of moderate hypercarbonemia showing maximum value of 50mmHg or more (equivalent to PaCO2> 45mmHg) during percutaneous anesthesia with intravenous anesthesia 4) Occurrence of hypoxemia showing 90% or less of the value of percutaneous oxygen saturation during intravenous anesthesia | — |
Secondary
| Measure | Time frame |
|---|---|
| 1) Anesthesia depth assessment (Ramsay scale) 2) Anesthesia dose | — |
Contacts
Nagasaki University Hospital