Study of sweating function with QSART in collagen diseases

Evaluation of sweating function in patients with collagen disease using the quantitative sudomotor axon reflex test (QSART): Study protocol for an investigator-initiated, prospective, observational clinical study

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

JPRN

Registry ID

JPRN-jRCTs072190009

Enrollment

100

Registered

2019-06-04

Start date

2019-07-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Collagen diseases

Interventions

Acetylcholine chloride is iontophoretically applied to the skin.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Collagen diseases (Systemic sclerosis, Mixed connective tissue disease, Systemic lupus erythematosus, Sjogren's syndrome, Dermatomyositis)

Exclusion criteria

Exclusion criteria: Patients who are incompatible for Ovisot. Patients who have troubles in the forearms. Patients who have serious allergy for dressing materials.

Design outcomes

Primary

Measure	Time frame
Axon reflex-mediated indirect sweat volume and latency time Raynaud's condition score	—

Secondary

Measure	Time frame
sex, age, disease, duration, history of digital ulcers, visceral changes, smoking, job, previous diseases, treatment, clinical data, presence of digital ulcers or pernio, degree of skin thickening, nail fold bleeding by dermoscope, presence of calcifications or telangiectasia, temprature of the fingers	—

Contacts

Public ContactMiwa Ashida

Nagasaki University Hospital

ashida@nagasaki-u.ac.jp+81-95-819-7333

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026