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The study of the control of postoperative Insulin resistance by preoperative oral carbohydrate and intravenous glucose administration during anesthesia.

The study of the control of postoperative insulin resistance by preoperative oral carbohydrate and intravenous glucose administration during anesthesia. - postoperative insulin resistance by preoperative oral carbohydrate and intravenous glucose administration during anesthesia.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-jRCTs072180081
Enrollment
20
Registered
2019-03-28
Start date
2015-12-07
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

jaw deformity

Interventions

glucose group (G): patients drink 278 ml of water with 50g glucose ( 178 ml of mineral water and 50 g glucose ( 100ml of 50% carbohydrate solution 200 ml) 2 hours before anesthesia and receive acetate

Sponsors

Tsukamoto Masanori
Lead Sponsor
Takeshi Yokoyama
Collaborator
NIKKISO CO.,LTD.
Collaborator

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. written informed concent is obtained from jaw deformity patients who undergo osteotomy 2. aged from 20 to 50 3. ASA 1 or 2 4. estimated operation time: more than 3 hours

Exclusion criteria

Exclusion criteria: 1. patients who have any other disorders except for jaw deformity 2. patients diagnosed with diabetes mellitus or disorder of carbohydrate metabolism 3. 18.0>BMI BMI<=30 4. patients whom reseachers consider inappropriate

Design outcomes

Primary

MeasureTime frame
Insulin resistance

Secondary

MeasureTime frame
blood test ( glucose, lactate, pyruvic acid, insulin, glucagon, free fatty acid,ketone body, catecholamine, 3-methylhistidine(indicator of muscle protein degradation,cortisol), serum electrolyte(Na+,K+,Mg2+,Ca2+,Cl-),arterial blood gas (pH,PaCO2,PaO2,HCO3-,BE),urine volume, urea nitrogen

Contacts

Public ContactSayuri Kadowaki

3-1-1 Maidashi Higashi-ku Fukuoka

s.koyama@dent.kyushu-u.ac.jp+81-92-642-6480

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026