Major duct excision (Microdochectomy) for abnormal nipple discharge guided by real time ICG fluorescence imaging technique

Status

Recruiting

Phases

Phase 2

Study type

Interventional

Source

JPRN

Registry ID

JPRN-jRCTs071240081

Enrollment

Registered

2024-12-05

Start date

2025-04-25

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

abnormal nipple discharge Ductal carinoma in situ(DCIS)

Interventions

Microdochectomy is performed to identify breast cancer with abnormal nipple discharge. First, the ducts with abnormal secretion are identified, cannulated, injected with dye (indigocarmine) and ICG in

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: (1) Patients who have abnormal nipple discharge for microdochectomy (2) Paticipants have completed the whriten informed consent for this study

Exclusion criteria

Exclusion criteria: (1) Paticipants who are allergic to the agents to be used (2) Paticipants who are deemed inappropriate as research subjects by the principal investigator and research coordinators

Design outcomes

Primary

Measure	Time frame
The accuracy rate of ICG fluorescence identificated the ducts and adenohypophysis areas causing nipple secretions.	—

Secondary

Measure	Time frame
1. Pathological diagnosis and surgical margin status 2. Safety events	—

Contacts

Public ContactRie Sugihara

Kurume University

sugihara_rie@kurume-u.ac.jp+81-942-35-3311

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026