Establishment of treatments to improve the endometrial microbiome

Status

Recruiting

Phases

Phase 2

Study type

Interventional

Source

JPRN

Registry ID

JPRN-jRCTs071220077

Enrollment

150

Registered

2022-12-06

Start date

2023-05-31

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

infertility

Interventions

Vaginal probiotics for endometrial dysbiosis

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: 1. Patients undergoing IVF and embryo transfer at our OB/GYN department. 2. Patient who have good frozen embryos by egg retrieval surgery. 3. Patient scheduled for a single embryo transfer.

Exclusion criteria

Exclusion criteria: 1. Patients with a diagnosis of chronic endometritis made by endometrial pathology. 2. Patients with ovarian Insufficiency. 3. Patients with endometrial polyps on hysteroscopy.

Design outcomes

Primary

Measure	Time frame
Effectiveness	—

Secondary

Measure	Time frame
Changes in the composition of Lactobacillus species in the endometrial microbiome.	—

Contacts

Public ContactSyuko Nakada

University of the Ryukyus Hospital

h200357@med.u-ryukyu.ac.jp+81-98-894-1301

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026