The study of pain relief by acetaminophen or NSAIDs for elderly patients with osteoarthritis

The study of pain relief by acetaminophen or NSAIDs for elderly patients with osteoarthritis of hip and knee - RETHINK

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-jRCTs071200112

Enrollment

400

Registered

2021-03-11

Start date

2021-05-07

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Osteoarthritis of the hip, Osteoarthritis of the knee

Interventions

Oral administration of analgesics

Acetaminophen

Anti-Inflammatory Agents, Non-Steroidal

Osteoarthritis, Hip

Osteoarthritis, Knee

NSAID

Osteoarthritis

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients with osteoarthritis over 65 years, and NRS>=3

Exclusion criteria

Exclusion criteria: Patients on medication for pain caused by causes other than osteoarthritis

Design outcomes

Primary

Measure	Time frame
Change in Numerical rating scale (0 = no pain, 10 = worst pain you can imagine) after 8 weeks	—

Secondary

Measure	Time frame
Change in NRS after 4 weeks Change in renal function value Changes in liver function values Incidence of gastrointestinal disorders Change in SF-8 Change in blood pressure safety	—

Contacts

Public ContactEndo Makoto

Kyushu University Hospital

makendo@ortho.med.kyushu-u.ac.jp+81-92-642-5488

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026