Acute Myocardial Infarction Acute Myocardial Infarction
Conditions
Interventions
After the treatments for the acute phase of myocardial Infarction,Ach-provocation test is performed for the patients that an agreement by a patient was provided.
The patients who are positive and nega
Sponsors
Kaikita Koichi
Ishii Masanobu
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: The patients with ST elevation and non-ST elevation myocardial infarction underwent primary percutaneous coronary intervention (PCI) using the drug eluting stent (DES) or bare metal stent (BMS), who meets all the following eligibility criteria. 1 The patients who are performed ACh-provocation test at 2 weeks after admission and no residual organic stenosis needing PCI 2 Man and woman at the range from 20-85years old at the time of informed consent 3 The case that informed consent by a patient was provided in a document
Exclusion criteria
Exclusion criteria: 1. Patient with unstable angina 2. Patients with triple vessel disease 3. Patients with left ventricular systolic dysfunction (Ejection fraction <40%) 4. Patients with chronic atrial fibrillation 5. Patients with severe liver dysfunction 6. Patients who are intolerable with dihydropyridine based calcium channel blockers 7. Patients with prior PCI using DES8 8. Patients whom the chief physician judged to be inappropriate for study enrollment
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| A rate of changes in ACh-provoked coronary constrictive response and degree of coronary vascular tone at the follow-up coronary angiogram at 6-12 months after primary PCI | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Incidence of coronary spasm at the 2nd ACh-provocation test 2. Changes in biomarkers 3. Cardiovascular events (cardiovascular death, non-fatal MI, unstable angina, rehospitalization for heart failure, re-PCI,etc) 4. Adverse effects 5. Coronary lesion finding by optical coherence tomography (OCT) (if possible) | — |
Contacts
Public ContactKoichi Kaikita
Kumamoto University Hospital
Outcome results
None listed