depression
Conditions
Sponsors
Okada Go
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients with major depressive (1) Aged 18-60 years old (2)Being diagnosed as depression (currently meeting the criteria for a depressive episode) according to DSM-5 criteria (3)Written consent for participation has been obtained from the participant him/herself
Exclusion criteria
Exclusion criteria: (1) Decisionally impaired individuals who has diminished capacity to understand the aim of the research (2) Physically impaired individuals who are not able to complete the experiment (3) Subjects who are contraindicated for the use of MRI Having an implanted heart pace-maker Having implanted cerebral (arteries) clips Having implanted neural/nerve stimulators Having implanted pumps Having work experience in a metal industry or possibility of metal residues remaining in the body Having metal-tattoos (including tattooed eye-lining) Being pregnant, or having possibility of being pregnant MRI claustrophobia (4)Those who have received NF, mECT, or rTMS within the past 1 year (5)Any individuals judged as inappropriate for the experiment by the principal investigator or a collaborating researcher.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The changes from baseline in the BDI-II 8-item subscore (related to depressive cognition) when conducting functional connectivity neurofeedback targeting functional connectivity associated with depressive cognition. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1 Depressive symptoms/Changes from baseline in the total scores of BDI-II and HRSD. 2 Social cognition/Changes from baseline in the performance on the emotional bias task. | — |
Contacts
Public ContactToshiharu Kamishikiryo
Hiroshima University
Outcome results
None listed