Abdominal surgery
Conditions
Interventions
A hypotension prediction index(HPI) is calculated by using the Acumen IQ sensor and the HemoSphere Advanced Monitoring Platform. When HPI exceeds 85, circulatory management during surgery is performed
Sponsors
Morimatsu Hiroshi
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1.Patient is 18 years or older at the time of consent (regardless of gender) 2.Patient is scheduled for intra-abdominal surgery under general anesthesia that is expected to last more than 120 minutes 3.Patient is scheduled for the use of an arterial blood pressure catheter 4.Serum creatinine (Cr) >=0.80mg/dL 5.Systolic blood pressure >=90mmHg 6.American Society of Anesthesiology (ASA) physical status classification II, III or IV 7.Patients who have received sufficient explanation and informed written consent of their own free will to participate in this study
Exclusion criteria
Exclusion criteria: 1.Patients undergoing urgent/emergency surgery 2.Patients suffering from sepsis (according to current Sepsis-3 definition) 3.Patients scheduled for nephrectomy, liver and/or kidney transplantation 4.Patients undergoing dialysis 5.Patients with atrial fibrillation 6.Patients with known intracardiac shunts 7.Patients with known moderate to severe valvular disease 8.Patients with known EF < 30% 9.Patients with a history of chronic heart failure 10.Patient participating in other interventional trials 11.Patients who are pregnant, breastfeeding, or possibly pregnant 12.Patients who are judged to be inappropriate for participation in this study by a local investigator
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Total time (minutes) below a mean arterial pressure (MAP) of 65 mmHg | — |
Secondary
| Measure | Time frame |
|---|---|
| 1.Incidence below a MAP of 65 mmHg 2.Time-weighted average mean arterial pressure below a MAP of 65 mmHg 3.Total time (minutes) and incidence below a MAP of 55 and 60 mmHg 4.Time-weighted average mean arterial pressure below a MAP of 55 and 60 mmHg 5.Area under the curve below a MAP of 55, 60, and 65 mmHg 6.Number of episodes below a MAP of 55, 60, and 65 mmHg 7.Minimum MAP (mmHg) 8.Incidence of postoperative acute kidney injury and delirium 9.30-day mortality after surgery 10.Compliance rate of intervention | — |
Contacts
Public ContactRyo Negayama
Okayama University Hospital
Outcome results
None listed