Laparotomy under general anesthesia
Conditions
Interventions
The study is performed during the induction of general anesthesia in general. After induction with propofol, remifentanil is administered continuously to achieve an effect site concentration of 2 ng/m
general anesthesia, MECK
Sponsors
Kamiya Satoshi
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: A) Cases in which the patient is at least 18 years of age at the time consent is obtained and in which laparotomy is scheduled to be performed under general anesthesia. B) Cases in which invasive radial arterial blood pressure monitering will be performed. C) Cases in which the patient's written consent to participate in this study is obtained.
Exclusion criteria
Exclusion criteria: A) Cases with atrial fibrillation or irregular R-R interval. B) Cases in which it is inappropriate to perform invasive radial arterial monitering. C) Patients with significant hemodynamic or neurologic impairment in the upper extremities. D) Patients with severe stenosis or occlusive lesions in cerebral vessels. E) Cases in which the use of remifentanil, propofol, or rocuronium is contraindicated. F) Cases in which the anesthesiologist in charge deems it inappropriate to conduct the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Difference between intervention group and external control group in the mean value of rate of change of blood pressure during surgical skin incision | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Evaluation of the equivalence of the high MECK group among the intervention group to the external control group 2. Blood pressure before surgical skin incision in the intervention group | — |
Contacts
Public ContactHiroki Sato
Hiroshima University Hospital
Outcome results
None listed