Pancreatic neuroendocrine neoplasms
Conditions
Interventions
Radiofrequency ablation for tumor under EUS-guidance
Sponsors
Matsumoto Kazuyuki
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Age more than 18 years old 2. Patient who have been fully informed consent. 3. Pathologically confirmed PNEN with grade by EUS-FNA (WHO 2017 classification) 4. Tumor size 15 mm or less on CE-CT 5. non-functionnal PNEN or insulinom
Exclusion criteria
Exclusion criteria: 1. Allergy for contrast medium 2. Placement of a cardiac pacemaker 3. Within 2 mm of the distance between tumor and main pancreatic duct on radiographic images 4. Suspect of lymph node metastasis or distant metastasis on CE-CT. 5. Less than 50% of PT or less than 1.5 of INR 6. Less than 50,000 per microliter of PLT 7. Less than 30 mL/min/1.73m2 of eGFR 8. Administeration of more than 2 antithrombotic agents 9. Not less than 2 of performance status 10. Being pregnant or possibly pregnant 11. Less than 5 years of estimated prognosis 12. Patients judged as inappropriate candidate by the chief medical examiner
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Safety | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Efficacy(1 and 6 months after procedure) 2. Detail of procedure 3. Failure of procedure equipment 4. Development or exacerbation of diabetes mellitus(6 months after procedure) 5. Survival at 6 months after procedure | — |
Contacts
Public ContactKazuyuki Matsumoto
Okayama University Hospital
Outcome results
None listed