Parkinson Disease Parkinson's disease, gait impairment, Freezing of G ait
Conditions
Interventions
In This study, participants asked to perform motor imagery training with neurofeedback, which provided as visual indicator based on the brain activities measured by the near-infrared spectroscopy medi
Neurofeedback , motor imagery
Sponsors
Mihara Masahito
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) patients who had written informed consent 2) age older than 39 year old 3) PD patients with diagnosis of clinically probable or clinically established PD in MDS criteria 4) Patients with Hoehn-Yahr stage 2 to 4 5) Patients who can walk 10 m safely with or without aid 6) Patients whose anti-Parkinsonian drug is not changed for at least 2 months at the time of registration 7) Patients who can understand the verbal order and perform task
Exclusion criteria
Exclusion criteria: 1) moderate to severe dmentia with MMSE score90%) 5) Patients wiht history of neurosurgical operation including Deep brain stimulation and trans-arterialaneurysm coil embolization) 6) Patients unstable in vital signs 7) Patients with corrected binocular visual acuity less than 1/20 8) Patients with scalp lesion which needed treatment 9) Women with Pregnancy, lactating, or suspected pregnancy 10) Patients who is unable to perform brain MRI scannning 11) Patients with past or current history of clinically established psychological illness (needs wnti-psychotic drugs). 12) Patients have experienced experimental brain stimulation intervention (including repetitive trans cranial magnetic stimuration or transcranial direct/alternative current stimulation) within 6 months prior to the enrollment. 13) Patients with severe, unpredicable wearing-off which disturb stable evaluation in each visit 14) Patients with muscloskeltal complication which affect gait performance 15) Patients assumed to be inadequate fore enrollment by their attending physician
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 10m walk test | — |
Secondary
| Measure | Time frame |
|---|---|
| 10m walk test, MDS-UPDRS, Mini-BESTest, 3m-Timued Up and Go test, FOGQ, PDQ8, number of falls, any adverse effect | — |
Contacts
Public ContactMasahito Mihara
Kawasaki Medical School Hospital
Outcome results
None listed