depression
Conditions
Interventions
A one-day NFB session takes about 45 minutes. The sessions are conducted 5 times within 2 weeks.
Sponsors
Okamoto Yasumasa
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: (1)Patients aged 20 years and over,under 80 years (outpatient or hospitalized patient). (2)Subjects are diagnosed with major depressive disorder according to DSM-TR or DSM-5. (3)Currently subjects meet diagnostic criteria for major depressive episodes (according to M.I.N.I.). (4)In the latest major depressive episodes,with treatment-resistant(HRSD score is 14 points or more with sufficient doses of antidepressants for 4 weeks or more) or with treatment low tolerance(impossible to take in adequate amount antidepressants by serious side effects). (5)Signed informed consent by oneself.
Exclusion criteria
Exclusion criteria: (1)Incapability to understand the purpose of the study. (2)Impossible to examine on the ground of serious illness. (3)It`s difficult for subjects below to get an MRI. - With an implanted cardiac pacemaker. - With a brain vascular clip. - Users of a nerve electrical stimulator. - With an implanted pump in one's body. - With a piece of metal in one's body. - With tattoos (including permanent makeup etc). - Pregnancy or possibly pregnant. - MRI claustrophobia. (4)Those participating in other intervention studies.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hamilton Rating Scale for Depression(HRSD) Beck Depression Inventory(BDI-II) The Positive and Negative Affect Schedule(PANAS) | — |
Secondary
| Measure | Time frame |
|---|---|
| Rumination Reflection Questionnaire(RRQ) Ruminative Response Scale(RRS) | — |
Contacts
Public ContactGo Okada
Hiroshima University Hospital
Outcome results
None listed